Katherine Noble was born on April 10, 1880 to Palmer and Martha (Libby) Noble in Calais, Maine. She graduated from Brattleboro Memorial Hospital in 1911 and spent six years doing private nursing. She then became District Nurse of Worcester, Massachusetts for about six years. She came to Southwest Harbor, Maine in September 1933 as Director of the Tremont / Southwest Harbor Nursing Service. She retired in May 1950 and died on March 18, 1971 in Calais, Maine.